Research Articles
Strategies for Mitigating Noise and Crosstalk in Synthetic Genetic Circuits: From Foundational Principles to Clinical Applications
Synthetic genetic circuits are revolutionizing biotechnology and therapeutic development, but their reliability is often compromised by noise and crosstalk, which can lead to unpredictable behavior and functional failure.
Mitigating Genetic Drift in Synthetic Biology: From Foundational Concepts to Advanced Control Strategies
This article provides a comprehensive framework for researchers, scientists, and drug development professionals to understand, manage, and counteract genetic drift in engineered biological systems.
Strategic Mitigation of Fitness Costs in Engineered Microbial Strains: From Foundational Concepts to Biomedical Applications
This article provides a comprehensive resource for researchers and drug development professionals on the critical challenge of fitness costs in engineered microbes.
Optimizing Synthetic Microbial Communities: From Foundational Ecology to Clinical Translation
This article provides a comprehensive roadmap for researchers, scientists, and drug development professionals seeking to optimize the function of Synthetic Microbial Communities (SynComs).
Harnessing Ecological Networks to Detect Influential Organisms: A Novel Framework for Sustainable Systems
This article explores the ecological-network-based approach for detecting organisms with disproportionate influence on system outcomes, a methodology with transformative potential for agriculture and drug discovery.
Metagenomic Insights into Coastal Extracellular Enzymes: From Microbial Ecology to Biomedical Potential
This article explores the transformative role of metagenomics in deciphering the diversity, function, and dynamics of extracellular enzymes in coastal waters.
Engineering Microbial Consortia: Division of Labor Strategies for Advanced Biomanufacturing and Therapeutics
This article explores the paradigm of engineering microbial consortia for division of labor, a transformative approach in synthetic biology that distributes complex biological tasks across specialized microbial subpopulations.
Harnessing Microbial Communities: Engineering Consortia for Sustainable Biotech Applications
This article explores the emerging field of community-level engineering, where designed microbial consortia are leveraged for advanced, sustainable biotechnological applications.
Harnessing Synthetic Microbial Consortia for Advanced Plastic Biodegradation: Strategies, Applications, and Future Directions
This article comprehensively examines the development and application of synthetic microbial consortia (SynComs) for plastic degradation, addressing a critical environmental challenge.
Unlocking Microbial Dark Matter: Diffusion-Based Cultivation for Novel Marine Bacteria and Drug Discovery
Over 99% of marine bacteria remain uncultured, representing a vast untapped reservoir of biodiversity and biotechnological potential.